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Dr. Andrea Sboner

Project Co-Investigator

Andrea Sboner, Ph.D., Director of Informatics and Computational Biology at the Englander Institute for Precision Medicine at Weill Cornell Medicine. Dr. Sboner’s main interest is the computational analysis of the human transcriptome and proteome and the computational and statistical analysis of the human genome using high-throughput experimental data to elucidate the complex mechanisms leading to cancer development and progression for close collaborations with molecular biologists and biomedical investigators to advance translational research.

His focus is in particular on next-generation sequencing applied to the transcriptome (RNASeq) and to the genome to elucidate the complex mechanisms leading to cancer development and progression. More specifically, he is interested in the role of genomic rearrangements in cancer. 

He developed the FusionSeq approach, which led to the discovery of novel gene fusions from RNA-seq in PCa and in a broad range of malignancies. FusionSeq enabled the first fusion ever discovered to involve a microRNA and is currently investigating the role of lncRNAs and non-coding mutations in PCA. Dr. Sboner has published multiple papers together with other SPORE investigators. Finally, Dr. Sboner is a member of the Encyclopedia of DNA Elements (ENCODE) effort and a co-author on several ENCODE papers.

Weill Cornell Medicine SPORE in Prostate Cancer Belfer Research Building
413 E. 69th St.
New York, NY 10021 Phone: (646) 962-6184